Rebecca Voorhees, Ph.D.
Assistant Professor, Heritage Principal investigator
voorhees [at] caltech.edu
Rebecca performed her graduate work in Venki Ramakrishnan’s lab at the Medical Research Council Laboratory of Molecular Biology (LMB), where she studied the molecular mechanism of protein synthesis using X-ray crystallography. For her postdoctoral studies, Rebecca joined Manu Hegde’s lab, just down the hall in the LMB’s Cell Biology division. In Manu’s lab Rebecca used single particle cryoelectron microscopy (cryo-EM) to study how secreted and integral membrane proteins are specifically targeted to the endoplasmic reticulum. Rebecca moved to Caltech in July 2017, where she joined the Division of Biology and Biological Engineering. Rebecca’s work has been recognized by the Searle Foundation, the Pew-Stewart Scholar’s program, the Shurl and Kay Curci Foundation and the Heritage Medical Research Institute.
Alison Inglis, Ph.D.
Alison received her undergraduate and masters degrees in biochemistry from Oxford and then joined Roger Williams’ lab at the Medical Research Council Laboratory of Molecular Biology in Cambridge. As a PhD student Alison used structural and biochemical strategies to dissect how amino acid starvation is first detected and then communicated in mammalian cells. Alison joined the lab in August 2018, and is studying membrane protein biogenesis.
Kurt Januszyk, Ph.D.
Kurt performed his graduate work at UCLA in Rob Clubb’s laboratory where he used solution NMR to study RNA structure. He then joined Chris Lima’s group at Sloan Kettering Cancer Center, where he relied on a combination of X-ray crystallography, in vitro biochemistry, and cryo-EM to study the RNA exosome. Kurt joined the Voorhees lab in April 2018, and is using cryo-EM to study mRNA quality control and translational regulation.
Graduate Student (Biochemistry and Molecular Biophysics option)
Cai earned her undergraduate degree in Biology from the National University of Singapore. Prior to starting her PhD she worked in the laboratory of Lu Gan using cryo-electron tomography to study chromosome segregation in yeast. Cai joined the Voorhees lab in May 2018, where she is using her electron microscopy experience to study the molecular mechanism of protein quality control.
roania [at] caltech.edu
Rob is a Southern California native, who spent several years in industry before working for twenty years as a technician in the Deshaies group at Caltech. He brings his extensive experience in yeast genetics and protein biochemistry to the Voorhees lab where Rob is responsible both for keeping the lab running and providing technical support to other group members.
Graduate Student (Chemistry option)
Katie earned her B.S. in Chemistry from Pomona College in Claremont, CA. Prior to starting her PhD, Katie worked in the laboratory of Jane Liu developing a platform to engineer new riboswitches. She also worked with Jacob Berlin and Greg Copeland at City of Hope synthesizing DNA-encoded small molecule combinatorial libraries. Katie joined the Voorhees lab in December 2018, where she is studying membrane protein biogenesis.
Tino Pleiner, Ph.D.
Tino studied biochemistry at the University of Leipzig and then joined Dirk Görlich’s group at the Max Planck Institute for Biophysical Chemistry in Göttingen where he earned his MSc and PhD. In the Görlich lab Tino developed a pipeline for rapid discovery and purification of nanobodies in collaboration with his on-site herd of alpacas. Tino joined the Voorhees lab in October 2017, where he is studying membrane protein quality control with the support of a Caltech BBE Divisional Postdoctoral fellowship.
Graduate Student (Biology option)
Ángel studied biochemistry as an undergraduate at the Universidad de Sevilla. Before starting his PhD at Caltech, he conducted research at the University of Dundee, University of Cambridge, and finally was a SURF student at Caltech in Bill Dunphy’s group. Ángel joined the Voorhees lab in December 2017, and is using cell biological and biochemical strategies to study mRNA quality control.
kzeigler [at] caltech.edu